Article
Classical markers like ER and ki-67, but also survivin and pERK, could be involved in the pathological response to gemcitabine, adriamycin and paclitaxel (GAT) in locally advanced breast cancer patients: results from the GEICAM/2002-01 phase II study.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Jun 2012
Sánchez-Rovira Pedro, Antón Antonio, Barnadas Agustí, Velasco Amalia, Lomas María, Rodríguez-Pinilla María, Ramírez José Luis, Ramírez César, Ríos María José, Castellá Eva, García-Andrade Carmen, San Antonio Belén, Carrasco Eva, Palacios José Luis
Abstract excerpt
INTRODUCTION: The identification and validation of biomarkers of chemotherapy sensitivity is critical in order to individualise therapy in breast cancer. We evaluated pathological complete response (pCR) to GAT, and its correlation with tumour biomarkers before and after neoadjuvant chemotherapy....
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