Article
Cloning of canine gastrin cDNA's encoding variant amino acid sequences.
Digestion - 1 Jan 1990
Gantz I, Takeuchi T, Yamada T
Abstract excerpt
We have isolated 2 clones encoding gastrin from a canine antral mucosa cDNA library. The clones differed in nucleotide sequence at 2 sites in the coding region. One of the clones confirmed the amino acid sequence of dog gastrin obtained by peptide purification and analysis. An A-G substitution in the other clone resulted in a Thr-Ala substitution in the region encoding the biologically active carboxyl-terminal...
Topics
- Amino Acid Sequence
- Animals
- Cloning, Molecular
- DNA
- Dogs
- Gastrins
- Genetic Variation
- Molecular Sequence Data
- Polymorphism, Genetic