Article
Bacteriophages with the ability to degrade uropathogenic Escherichia coli biofilms.
Viruses - 1 Apr 2012
Chibeu Andrew, Lingohr Erika J, Masson Luke, Manges Amee, Harel Josée, Ackermann Hans-W, Kropinski Andrew M, Boerlin Patrick
Abstract excerpt
Escherichia coli-associated urinary tract infections (UTIs) are among the most common bacterial infections in humans. UTIs are usually managed with antibiotic therapy, but over the years, antibiotic-resistant strains of uropathogenic E. coli (UPEC) have emerged. The formation of biofilms further complicates the treatment of these infections by making them resistant to killing by the host immune system as well as...
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