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Autophagy and cardiovascular aging

31 May 2012

Abstract excerpt

The biological aging process is commonly associated with increased risk of cardiovascular diseases. Several theories have been put forward for aging-associated deterioration in ventricular function, including attenuation of growth hormone (insulin-like growth factors and insulin) signaling, loss of DNA replication and repair, histone acetylation and accumulation of reactive oxygen species. Recent evidence has...

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PMID: 22580468
DOI: 10.4161/cc.20317

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