Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Noninvasive prenatal detection of chromosomal aneuploidies using different next generation sequencing strategies and algorithms

9 May 2012

Abstract excerpt

OBJECTIVE: Here we describe the successful application of massively parallel sequencing for noninvasive prenatal detection of trisomy 21. In addition, for the detection of a broader spectrum of fetal aneuploidies, a target enrichment approach was successfully tested. METHODS: The circulating cell-free DNA was prepared from 53 maternal blood samples and analysed using Illumina's sequencing systems Genome...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Syndromes and Imprinting
Share to Genomic variations and chromosomal abnormalities
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22573401
DOI: 10.1002/pd.3862

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Noninvasive prenatal detection of chromosomal aneuploidies using different next generation sequencing strategies and algorithmsPMID 22573401Read ↗

High-Throughput Massively Parallel Sequencing for Fetal Aneuploidy Detection from Maternal PlasmaSemantic proximity Read ↗

Genome-Wide Fetal Aneuploidy Detection by Maternal Plasma DNA SequencingSemantic proximity Read ↗

Noninvasive Prenatal Testing for Fetal AneuploidySemantic proximity Read ↗

Diagnostic accuracy of random massively parallel sequencing for non-invasive prenatal detection of common autosomal aneuploidies: a collaborative study in EuropeSemantic proximity Read ↗

A robust second‐generation genome‐wide test for fetal aneuploidy based on shotgun sequencing cell‐free DNA in maternal bloodSemantic proximity Read ↗

Non-Invasive Prenatal Chromosomal Aneuploidy Testing - Clinical Experience: 100,000 Clinical SamplesSemantic proximity Read ↗

Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasmaSemantic proximity Read ↗

Noninvasive prenatal screening for fetal trisomies 21, 18, 13 and the common sex chromosome aneuploidies from maternal blood using massively parallel genomic sequencing of DNASemantic proximity Read ↗

DNA Sequencing versus Standard Prenatal Aneuploidy ScreeningSemantic proximity Read ↗

Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity studySemantic proximity Read ↗

Non‐invasive prenatal testing for fetal aneuploidy: charting the course from clinical validity to clinical utilitySemantic proximity Read ↗

Non‐invasive prenatal testing for trisomies 21, 18 and 13: clinical experience from 146 958 pregnanciesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.