Article
Characterization of the HLA-C*07:01:01G allele group in European and African-American cohorts.
Human immunology - 1 Jul 2012
Deng Zhihui, Gao Xiaojiang, Kirk Gregory D, Wolinsky Steven, Carrington Mary
Abstract excerpt
The HLA-C*07:01:01G allele group consists of three nonsynonymous alleles, C*07:01:01, C*07:06 and C*07:18, plus C*07:01:02, which is synonymous to C*07:01:01. All of these alleles have identical exons 2, 3 and 4, but differ in exons 5 or 6. Therefore routine sequence-based typing (SBT) of exons 2 and 3 is unable to resolve these subtypes, resulting in ambiguous typing results in population and disease cohort...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
