Article
MEN1 and pituitary adenomas.
Annales d'endocrinologie - 1 Apr 2012
Delemer Brigitte
Abstract excerpt
MEN1 gene mutations predispose carriers to pituitary tumors. Molecular pathways involved in the development of these tumors seem different to what is known in sporadic tumors. Clinical studies showed that all types of adenomas can be found with a predominance of prolactinoma and macroadenoma compared to a control population. These MEN1 tumors seem more aggressive, invasive and resistant to treatment requiring a...
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