Article
A perturbation in glutathione biosynthesis disrupts endoplasmic reticulum morphology and secretory membrane traffic in Arabidopsis thaliana.
The Plant journal : for cell and molecular biology - 1 Sept 2012
Au Kenneth K C, Pérez-Gómez José, Neto Hélia, Müller Christopher, Meyer Andreas J, Fricker Mark D, Moore Ian
Abstract excerpt
To identify potentially novel and essential components of plant membrane trafficking mechanisms we performed a GFP-based forward genetic screen for seedling-lethal biosynthetic membrane trafficking mutants in Arabidopsis thaliana. Amongst these mutants, four recessive alleles of GSH2, which encodes glutathione synthase (GSH2), were recovered. Each allele was characterized by loss of the typical polygonal...
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