Article
The interleukin 4 receptor gene and its role in recurrent airway obstruction in Swiss Warmblood horses.
Animal genetics - 1 Aug 2012
Klukowska-Rötzler J, Swinburne J E, Drögemüller C, Dolf G, Janda J, Leeb T, Gerber V
Abstract excerpt
Recurrent airway obstruction (RAO) in horses is the result of an interaction of genetic and environmental factors and shares many characteristics with human asthma. Many studies have suggested that the interleukin-4 receptor gene (IL4R) is associated with this disease, and a QTL region on chromosome 13 containing IL4R was previously detected in one of the two Swiss Warmblood families. We sequenced the entire IL4R...
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