[The diversity of aging models].

doi:10.1051/medsci/2012283018

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Article

[The diversity of aging models].

Medecine sciences : M/S - 1 Mar 2012

Galas Simon, Château Marie-Thérèse, Pomiès Pascal, Wang Jing, Menardo Julien, Puel Jean-Luc, Hugnot Jean-Philippe, Verdier Jean-Michel, Devau Gina

Abstract excerpt

Most of the signalling pathways involved in aging regulation have been recently found well conserved at various levels throughout the evolution. Taking this into account, a diversity of model organisms, including worms, rodents, and lemurs as well, allows to address different questions: how to understand the interactions between genetic and environmental factors while challenging theories of aging, to preserve...

Topics

Aging
Alzheimer Disease
Animals
Brain
Caenorhabditis elegans
Cellular Senescence
Cheirogaleidae
Cochlea
Disease Models, Animal
Gene Expression Profiling
Genetic Predisposition to Disease
Humans
Longevity
Mice
Mice, Inbred C57BL

Source

Open in PubMed

Identifiers

PMID: 22480654
DOI: 10.1051/medsci/2012283018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Neurologic Mutants

Models, Biological

Neural Stem Cells