Development of the hip in multiple epiphyseal dysplasia. Natural history and susceptibility to premature osteoarthritis.

Abstract excerpt

We have determined the natural history of hip development in 42 patients with multiple epiphyseal dysplasia (MED). Premature osteoarthritis was a frequent outcome and was almost inevitable before the age of 30 years in those with incongruent hips. There were two types of immature hips: type I, the more severe form, had a fragmented and flattened ossific nucleus and acetabular dysplasia, was misshapen at skeletal...

Topics

• Adult
• Discriminant Analysis
• Female
• Genetic Predisposition to Disease
• Hip Joint
• Humans
• Incidence
• Male
• Osteoarthritis, Hip
• Osteochondrodysplasias
• Prognosis