Article
Comparability of imazapyr-resistant Arabidopsis created by transgenesis and mutagenesis.
Transgenic research - 1 Dec 2012
Schnell Jaimie, Labbé Hélène, Kovinich Nik, Manabe Yuzuki, Miki Brian
Abstract excerpt
The Arabidopsis CSR1 gene codes for the enzyme acetohydroxyacid synthase (AHAS, EC 2.2.1.6), also known as acetolactate synthase, which catalyzes the first step in branched-chain amino acid biosynthesis. It is inhibited by several classes of herbicides, including the imidazolinone herbicides, such as imazapyr; however, a substitution mutation in csr1-2 (Ser-653-Asn) confers selective resistance to the...
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