Article
Preimplantation genetic diagnosis for HLA typing in a case of X-linked chronic granulomatous disease.
Acta obstetricia et gynecologica Scandinavica - 1 Jul 2012
Degn Birte, Hindkjaer Johnny, Christensen Mette Wulff, Mortensen Tanja Østerlund, Ingerslev Hans Jakob
Abstract excerpt
Bone marrow transplantation may be life saving in cases of hematopoietic disease, severe congenital immunodeficiency or malignancy. An HLA-matching sibling often gives the best success, but this may not be an option, nor may an HLA-matching unrelated donor be found. Preimplantation genetic diagnosis with HLA-matching embryos may then be a solution. We report the first Danish child born after such diagnosis with...
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