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Article

Hypoxia activates nucleus tractus solitarii neurons projecting to the paraventricular nucleus of the hypothalamus.

American journal of physiology. Regulatory, integrative and comparative physiology - 15 May 2012

King T Luise, Heesch Cheryl M, Clark Catharine G, Kline David D, Hasser Eileen M

Abstract excerpt

Peripheral chemoreceptor afferent information is sent to the nucleus tractus solitarii (nTS), integrated, and relayed to other brain regions to alter cardiorespiratory function. The nTS projects to the hypothalamic paraventricular nucleus (PVN), but activation and phenotype of these projections during chemoreflex stimulation is unknown. We hypothesized that activation of PVN-projecting nTS neurons occurs...

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Identifiers

PMID: 22403798
DOI: 10.1152/ajpregu.00028.2012
PMCID: PMC3362152

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