Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cardiac channelopathy causing sudden death as revealed by molecular autopsy.

International journal of legal medicine - 1 Jan 2013

Kauferstein Silke, Kiehne Nadine, Peigneur Steve, Tytgat Jan, Bratzke Hansjürgen

Abstract excerpt

BACKGROUND: Mutations in cardiac ion channel genes have been identified to cause sudden unexplained deaths (SUD), and polymorphisms have also been suggested to be risk factors. Therefore, postmortem genetic testing has become an important tool in elucidating the cause of death. METHODS AND RESULTS: In a sudden death case, a LQT-3-associated mutation (Il768V) in the cardiac sodium channel gene SCN5A was detected...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Anesthetics, Local

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Death, Sudden, Cardiac

Share to Forensic Genetics

Share to Heterozygote

Share to Injections

Share to NAV1.5 Voltage-Gated Sodium Channel

Share to Ryanodine Receptor Calcium Release Channel

Source

Identifiers

PMID: 22370996
DOI: 10.1007/s00414-012-0679-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cardiac channelopathy causing sudden death as revealed by molecular autopsy.PMID 22370996Read ↗

From Death to Life/Back to the Future: Detailed Premorbid Clinical and Family History Can Save Lives and Address the Final Diagnosis in Sudden Unexplained Deaths With Negative Autopsy.Semantic proximity Read ↗

Ion channelopathies associated genetic variants as the culprit for sudden unexplained death.Semantic proximity Read ↗

Mutations in the SCN5A gene: evidence for a link between long QT syndrome and sudden death?Semantic proximity Read ↗

The role of molecular autopsy in unexplained sudden cardiac death.Semantic proximity Read ↗

Cardiac channelopathy testing in 274 ethnically diverse sudden unexplained deaths.Semantic proximity Read ↗

[Application of molecular autopsy in sudden death caused by inherited arrhythmia].Semantic proximity Read ↗

Targeted next generation sequencing application in cardiac channelopathies: Analysis of a cohort of autopsy-negative sudden unexplained deaths.Semantic proximity Read ↗

Postmortem long QT syndrome genetic testing for sudden unexplained death in the young.Semantic proximity Read ↗

Cardiac channel molecular autopsy: insights from 173 consecutive cases of autopsy-negative sudden unexplained death referred for postmortem genetic testing.Semantic proximity Read ↗

Molecular autopsy of sudden unexplained death in the young.Semantic proximity Read ↗

Postmortem molecular analysis in victims of sudden unexplained death.Semantic proximity Read ↗

Sudden infant death syndrome: how significant are the cardiac channelopathies?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.