Article
Role of ATG8 and Autophagy in Programmed Nuclear Degradation in Tetrahymena thermophila
25 Feb 2012
Abstract excerpt
Autophagy is an evolutionarily conserved mechanism for the degradation of cellular components, but its role in enucleation during differentiation has not been established. Tetrahymena thermophila is a unicellular eukaryote with two functionally distinct nuclei, the somatic (macro-) and the germ line (micro-) nuclei. These nuclei are produced during sexual reproduction (conjugation), which involves differentiation...
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