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Article

DRD4 polymorphism moderates the effect of alcohol consumption on social bonding.

PloS one - 1 Jan 2012

Creswell Kasey G, Sayette Michael A, Manuck Stephen B, Ferrell Robert E, Hill Shirley Y, Dimoff John D

Abstract excerpt

Development of interpersonal relationships is a fundamental human motivation, and behaviors facilitating social bonding are prized. Some individuals experience enhanced reward from alcohol in social contexts and may be at heightened risk for developing and maintaining problematic drinking. We employed a 3 (group beverage condition) ×2 (genotype) design (N = 422) to test the moderating influence of the dopamine D4...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22347363
DOI: 10.1371/journal.pone.0028914
PMCID: PMC3275561

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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