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Article

Gene expression and stress response mediated by the epigenetic regulation of a transposable element small RNA.

PLoS genetics - 1 Feb 2012

McCue Andrea D, Nuthikattu Saivageethi, Reeder Sarah H, Slotkin R Keith

Abstract excerpt

The epigenetic activity of transposable elements (TEs) can influence the regulation of genes; though, this regulation is confined to the genes, promoters, and enhancers that neighbor the TE. This local cis regulation of genes therefore limits the influence of the TE's epigenetic regulation on the genome. TE activity is suppressed by small RNAs, which also inhibit viruses and regulate the expression of genes. The...

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PMID: 22346759
DOI: 10.1371/journal.pgen.1002474
PMCID: PMC3276544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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