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Article

Understanding and recognizing the Pelger-Huët anomaly.

American journal of clinical pathology - 1 Mar 2012

Colella Rita, Hollensead Sandra C

Abstract excerpt

The Pelger-Huët anomaly (PHA) is a recognized morphologic variant affecting all granulocytes but is most evident in polymorphonuclear neutrophils (PMNs). PHA is caused by a decreased amount of the lamin B receptor (LBR). Recognition of PHA morphologic features serves as a marker for mutations in...

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Source

Identifiers

PMID: 22338047
DOI: 10.1309/AJCP3G8MDUXYSCID

Genes

LBR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22338047-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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