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Article

Metabolomic analysis reveals that carnitines are key regulatory metabolites in phase transition of the locusts.

Proceedings of the National Academy of Sciences of the United States of America - 28 Feb 2012

Wu Rui, Wu Zeming, Wang Xianhui, Yang Pengcheng, Yu Dan, Zhao Chunxia, Xu Guowang, Kang Le

Abstract excerpt

Phenotypic plasticity occurs prevalently and plays a vital role in adaptive evolution. However, the underlying molecular mechanisms responsible for the expression of alternate phenotypes remain unknown. Here, a density-dependent phase polyphenism of Locusta migratoria was used as the study model to identify key signaling molecules regulating the expression of phenotypic plasticity. Metabolomic analysis, using...

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Identifiers

PMID: 22328148
DOI: 10.1073/pnas.1119155109
PMCID: PMC3295283

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