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Human skin pigmentation, migration and disease susceptibility

6 Feb 2012

Abstract excerpt

Human skin pigmentation evolved as a compromise between the conflicting physiological demands of protection against the deleterious effects of ultraviolet radiation (UVR) and photosynthesis of UVB-dependent vitamin D(3). Living under high UVR near the equator, ancestral Homo sapiens had skin rich in protective eumelanin. Dispersals outside of the tropics were associated with positive selection for depigmentation...

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PMID: 22312045
DOI: 10.1098/rstb.2011.0308

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