Article
Molecular links between endometriosis and cancer.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Aug 2012
Pollacco Joel, Sacco Keith, Portelli Mark, Schembri-Wismayer Pierre, Calleja-Agius Jean
Abstract excerpt
Endometriosis is the leading cause of morbidity among premenopausal women affecting about 1 in 10 females. The features shared by endometriosis and cancer include the ability to evade apoptosis, the stem cell-like ability and angiogenic potential. As such characteristics are encoded by the cell's genetic constitution, acquired mutations are responsible for the malignant transformation of endometriosis. Indeed, a...
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