Article
Salmonella enterotoxin (Stn) regulates membrane composition and integrity.
Disease models & mechanisms - 1 Jul 2012
Nakano Masayuki, Yamasaki Eiki, Ichinose Akitoyo, Shimohata Takaaki, Takahashi Akira, Akada Junko K, Nakamura Kazuyuki, Moss Joel, Hirayama Toshiya, Kurazono Hisao
Abstract excerpt
The mechanism of action of Salmonella enterotoxin (Stn) as a virulence factor in disease is controversial. Studies of Stn have indicated both positive and negative effects on Salmonella virulence. In this study, we attempted to evaluate Stn function and its effects on Salmonella virulence. To investigate Stn function, we first performed in vitro and in vivo analysis using mammalian cells and a murine ileal loop...
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