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Article

Overreliance on the Hexon Gene, Leading to Misclassification of Human Adenoviruses

2 Feb 2012

Abstract excerpt

The genome of human adenovirus (HAdV) D30 was sequenced in depth. Sequence assembly and analysis revealed two distinct viral sequences with identical hexon genes, which were the same as the one previously reported for HAdV-D30. However, one of the two viruses was found to be a recombinant of HAdV-D29. Exclusive reliance on serum neutralization can lead to mischaracterization of adenoviruses and miss coinfections....

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PMID: 22301156
DOI: 10.1128/jvi.06969-11

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