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Article

Predicted effect of direct acting antivirals in the current HIV-HCV-coinfected population in Spain.

Antiviral therapy - 1 Jan 2012

Poveda Eva, Vispo Eugenia, Barreiro Pablo, de Mendoza Carmen, Labarga Pablo, Fernández-Montero José Vicente, Martin-Carbonero Luz, Soriano Vincent

Abstract excerpt

BACKGROUND: Direct acting antivirals (DAAs) against HCV are eagerly awaited for HIV-HCV-coinfected individuals. However, the activity of first generation drugs is limited to HCV genotype 1 and is lower in cirrhotics, subtype 1a infections, prior interferon (IFN)-α exposure or unfavourable IL28B alleles. Herein, we report the current profile of HIV-HCV-coinfected patients at our institution in an attempt to...

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PMID: 22293607
DOI: 10.3851/IMP1992

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