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Article

Pupillometry in congenital central hypoventilation syndrome (CCHS): quantitative evidence of autonomic nervous system dysregulation.

Pediatric research - 1 Mar 2012

Patwari Pallavi P, Stewart Tracey M, Rand Casey M, Carroll Michael S, Kuntz Nancy L, Kenny Anna S, Brogadir Cindy D, Weese-Mayer Debra E

Abstract excerpt

INTRODUCTION: Congenital central hypoventilation syndrome (CCHS) is characterized by alveolar hypoventilation, autonomic nervous system (ANS) dysregulation (ANSD), and mutations in the paired-like homeobox 2B (PHOX2B) gene. ANSD in CCHS affects multiple systems and includes ophthalmologic abnormalities. We hypothesized that quantitative pupil measures, obtained using pupillometry, would vary between cases with...

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PMID: 22278185
DOI: 10.1038/pr.2011.38

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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