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Article

Autophagy and mitochondria in Pompe disease: Nothing is so new as what has long been forgotten

17 Jan 2012

Abstract excerpt

Macroautophagy (often referred to as autophagy) is an evolutionarily conserved intracellular system by which macromolecules and organelles are delivered to lysosomes for degradation and recycling. Autophagy is robustly induced in response to starvation in order to generate nutrients and energy through the lysosomal degradation of cytoplasmic components. Constitutive, basal autophagy serves as a quality control...

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PMID: 22253254
DOI: 10.1002/ajmg.c.31317

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