Article
Impaired puberty, fertility, and final stature in 45,X/46,XY mixed gonadal dysgenetic patients raised as boys.
European journal of endocrinology - 1 Apr 2012
Martinerie Laetitia, Morel Yves, Gay Claire-Lise, Pienkowski Catherine, de Kerdanet Marc, Cabrol Sylvie, Lecointre Claudine, Coutant Regis, Baron Sabine, Colle Michel, Brauner Raja, Thibaud Elisabeth, Leger Juliane, Nihoul-Fekete Claire, Bouvattier Claire
Abstract excerpt
CONTEXT: Gender assignment followed by surgery and hormonal therapy is a difficult decision in the management of 45,X/46,XY patients with abnormal external genitalia at birth considering the paucity of studies evaluating pubertal development and fertility outcome, most notably for patients raised as boys. OBJECTIVE: The purpose of this study was to describe the pubertal course of 20 45,X/46,XY patients born with...
Topics
- Adolescent
- Adult
- Body Height
- Child
- Child Rearing
- Follow-Up Studies
- Gonadal Dysgenesis, Mixed
- Growth Disorders
- Humans
- Infertility, Male
- Male
- Middle Aged
- Phenotype