Has there been a change in the natural history of Crohn's disease? Surgical rates and medical management in a population-based inception cohort from Western Hungary between 1977-2009.

doi:10.1038/ajg.2011.448

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Has there been a change in the natural history of Crohn's disease? Surgical rates and medical management in a population-based inception cohort from Western Hungary between 1977-2009.

The American journal of gastroenterology - 1 Apr 2012

Lakatos Peter Laszlo, Golovics Petra Anna, David Gyula, Pandur Tunde, Erdelyi Zsuzsanna, Horvath Agnes, Mester Gabor, Balogh Mihaly, Szipocs Istvan, Molnar Csaba, Komaromi Erzsebet, Veres Gabor, Lovasz Barbara Dorottya, Szathmari Miklos, Kiss Lajos S, Lakatos Laszlo

Abstract excerpt

OBJECTIVES: Medical therapy for Crohn's disease (CD) has changed significantly over the past 20 years with increasing use of immunosuppressives. In contrast, surgery rates are still high and there is little evidence that disease outcomes for CD have changed over the past decades. The objective of this study was to analyze the evolution of the surgical rates and medical therapy in the population-based Veszprem...

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PMID: 22233693
DOI: 10.1038/ajg.2011.448

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