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Article

Phenotypes and enviromental factors: their influence in PCOS.

Current pharmaceutical design - 1 Jan 2012

Diamanti-Kandarakis Evanthia, Christakou Charikleia, Marinakis Evangelos

Abstract excerpt

Polycystic ovary syndrome (PCOS) is a complex syndrome of unclear etiopathogenesis characterized by heterogeneity in phenotypic manifestations. The clinical phenotype of PCOS includes reproductive and hormonal aberrations, namely anovulation and hyperandrogenism, which coexist with metabolic disturbances. Reflecting the crosstalk between the reproductive system and metabolic tissues, obesity not only deteriorates...

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PMID: 22229564
DOI: 10.2174/138161212799040457

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