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Article

Analysis of the duplicated human C4/P450c21/X gene cluster.

The Journal of steroid biochemistry and molecular biology - 1 Dec 1992

Miller W L, Gitelman S E, Bristow J, Morel Y

Abstract excerpt

Gene duplications, deletions and rearrangements occur with an unusually high frequency in the region of the P450c21 genes encoding 21-hydroxylase. In the human genome, the locus contains at least 6 genes, oriented 5' C4A, P450c21A, XA, C4B, P450c21B, XB 3'. Sequence analysis of the XA gene, of the 5' flanking DNA of the C4A gene, and of part of the XB gene revealed that this gene cluster was duplicated by...

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PMID: 22217841
DOI: 10.1016/0960-0760(92)90324-C

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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