Article
A study on the relationship between TCTA tetranucleotide polymorphism of the HPRT gene and primary hyperuricemia.
Genetics and molecular research : GMR - 15 Dec 2011
Zhu Y S, Wei S G, Sun R F, Feng J L, Kuang W J, Lai J H, Li S B
Abstract excerpt
We examined polymorphism of the TCTA tetranucleotide sequence in the 3rd intron of the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene in the Han population of Ningxia Province in China. We also looked for a possible relationship between STR polymorphism in the 3rd intron of the HPRT gene and primary hyperuricemia. We used Chelex-100 to extract DNA, then PCR, PAGE and silver staining for allele...
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