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Article

False-negative ¹²³I-MIBG SPECT is most commonly found in SDHB-related pheochromocytoma or paraganglioma with high frequency to develop metastatic disease.

Endocrine-related cancer - 1 Feb 2012

Fonte Jay S, Robles Jeremyjones F, Chen Clara C, Reynolds James, Whatley Millie, Ling Alexander, Mercado-Asis Leilani B, Adams Karen T, Martucci Victoria, Fojo Tito, Pacak Karel

Abstract excerpt

The purpose of this study was to present the characteristics and outcome of patients with proven pheochromocytoma or paraganglioma who had false-negative iodine-123 metaiodobenzylguanidine single photon emission computed tomography ((123)I-MIBG SPECT). Twenty-one patients with false-negative (123)I-MIBG SPECT (7 males, 14 females), aged 13-55 years (mean: 41.40 years), were included. We classified them as...

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Source

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Identifiers

PMID: 22167067
DOI: 10.1530/ERC-11-0243
PMCID: PMC3420013

Genes

SDHB
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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