Article
High-level cefixime- and ceftriaxone-resistant Neisseria gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure.
Antimicrobial agents and chemotherapy - 1 Mar 2012
Unemo Magnus, Golparian Daniel, Nicholas Robert, Ohnishi Makoto, Gallay Anne, Sednaoui Patrice
Abstract excerpt
Recently, the first Neisseria gonorrhoeae strain (H041) highly resistant to the expanded-spectrum cephalosporins (ESCs) ceftriaxone and cefixime, which are the last remaining options for first-line gonorrhea treatment, was isolated in Japan. Here, we confirm and characterize a second strain (F89) with high-level cefixime and ceftriaxone resistance which was isolated in France and most likely caused a treatment...
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