Article
Systems cancer medicine: towards realization of predictive, preventive, personalized and participatory (P4) medicine.
Journal of internal medicine - 1 Feb 2012
Tian Q, Price N D, Hood L
Abstract excerpt
A grand challenge impeding optimal treatment outcomes for patients with cancer arises from the complex nature of the disease: the cellular heterogeneity, the myriad of dysfunctional molecular and genetic networks as results of genetic (somatic) and environmental perturbations. Systems biology, with its holistic approach to understanding fundamental principles in biology, and the empowering technologies in...
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