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Article

A Metaproteomic Approach to Study Human-Microbial Ecosystems at the Mucosal Luminal Interface

21 Nov 2011

Abstract excerpt

Aberrant interactions between the host and the intestinal bacteria are thought to contribute to the pathogenesis of many digestive diseases. However, studying the complex ecosystem at the human mucosal-luminal interface (MLI) is challenging and requires an integrative systems biology approach. Therefore, we developed a novel method integrating lavage sampling of the human mucosal surface, high-throughput...

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PMID: 22132074
DOI: 10.1371/journal.pone.0026542

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