Common oxytocin receptor gene (OXTR) polymorphism and social support interact to reduce stress in humans.

doi:10.1073/pnas.1113079108

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Article

Common oxytocin receptor gene (OXTR) polymorphism and social support interact to reduce stress in humans.

Proceedings of the National Academy of Sciences of the United States of America - 13 Dec 2011

Chen Frances S, Kumsta Robert, von Dawans Bernadette, Monakhov Mikhail, Ebstein Richard P, Heinrichs Markus

Abstract excerpt

The neuropeptide oxytocin has played an essential role in the regulation of social behavior and attachment throughout mammalian evolution. Because recent studies in humans have shown that oxytocin administration reduces stress responses and increases prosocial behavior, we investigated whether a common single nucleotide polymorphism (rs53576) in the oxytocin receptor gene (OXTR) might interact with...

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Identifiers

PMID: 22123970
DOI: 10.1073/pnas.1113079108
PMCID: PMC3250137

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OXTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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