Preventing Vitamin D Deficiency in Pregnancy – Importance for the Mother and Child

Abstract excerpt

Circulating maternal concentrations of hormonally active vitamin D [calcitriol, 1,25(OH)(2)D] rise early in the first trimester, doubling by the end of the third trimester. The early rise in calcitriol is believed to be necessary for enabling the immunological adaptation by the mother required for the maintenance of a normal pregnancy. This immunological adaptation is characterized by downregulation of the T...

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