Article
Controlled release of bone morphogenetic protein 2 and dexamethasone loaded in core-shell PLLACL-collagen fibers for use in bone tissue engineering.
Acta biomaterialia - 1 Feb 2012
Su Yan, Su Qianqian, Liu Wei, Lim Marcus, Venugopal Jayarama Reddy, Mo Xiumei, Ramakrishna Seeram, Al-Deyab Salem S, El-Newehy Mohamed
Abstract excerpt
Electrospun nanofibers mimic the native extracellular matrix of bone and have generated considerable interest in bone tissue regeneration. The aim of this study was to fabricate novel poly(l-lactide-co-caprolactone) (PLLACL), PLLACL/collagen nanofibers blended with bone morphogenetic protein 2 (BMP2) and dexamethasone (DEX) for controlled release during bone tissue engineering (BTE). The morphology, surface...
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