Article
Maternal synchronization of gestational length and lung maturation.
PloS one - 1 Jan 2011
Besnard Valérie, Wert Susan E, Ikegami Machiko, Xu Yan, Heffner Caleb, Murray Stephen A, Donahue Leah Rae, Whitsett Jeffrey A
Abstract excerpt
Among all mammals, fetal growth and organ maturation must be precisely synchronized with gestational length to optimize survival at birth. Lack of pulmonary maturation is the major cause of infant mortality in preterm birth. Whether fetal or maternal genotypes influence the close relationship between the length of gestation and lung function at birth is unknown. Structural and biochemical indicators of pulmonary...
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