Article
Pathogenesis and phylogenetic analyses of canine distemper virus strain ZJ7 isolate from domestic dogs in China.
Virology journal - 16 Nov 2011
Tan Bin, Wen Yong-Jun, Wang Feng-Xue, Zhang Shu-Qin, Wang Xiu-Dong, Hu Jia-Xin, Shi Xin-Chuan, Yang Bo-Chao, Chen Li-Zhi, Cheng Shi-Peng, Wu Hua
Abstract excerpt
A new isolate of canine distemper virus (CDV), named ZJ7, was isolated from lung tissues of a dog suspected with CDV infection using MDCK cells. The ZJ7 isolate induced cytopathogenic effects of syncytia in MDCK cell after six passages. In order to evaluate pathogenesis of ZJ7 strain, three CDV sero-negative dogs were intranasally inoculated with its virus suspension. All infected dogs developed clinical signs of...
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