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Article

Circulation of different lineages of dengue virus type 2 in Central America, their evolutionary time-scale and selection pressure analysis.

PloS one - 1 Jan 2011

Añez Germán, Morales-Betoulle Maria E, Rios Maria

Abstract excerpt

Dengue is caused by any of the four serotypes of dengue virus (DENV-1 to 4). Each serotype is genetically distant from the others, and each has been subdivided into different genotypes based on phylogenetic analysis. The study of dengue evolution in endemic regions is important since the diagnosis is often made by nucleic acid amplification tests, which depends upon recognition of the viral genome target, and...

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Identifiers

PMID: 22076162
DOI: 10.1371/journal.pone.0027459
PMCID: PMC3208639

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