Article
Perivascular human endometrial mesenchymal stem cells express pathways relevant to self-renewal, lineage specification, and functional phenotype.
Biology of reproduction - 1 Feb 2012
Spitzer Trimble L B, Rojas Angela, Zelenko Zara, Aghajanova Lusine, Erikson David W, Barragan Fatima, Meyer Michelle, Tamaresis John S, Hamilton Amy E, Irwin Juan C, Giudice Linda C
Abstract excerpt
Human endometrium regenerates on a cyclic basis from candidate stem/progenitors whose genetic programs are yet to be determined. A subpopulation of endometrial stromal cells, displaying key properties of mesenchymal stem cells (MSCs), has been characterized. The endometrial MSC (eMSC) is likely the precursor of the endometrial stromal fibroblast. The goal of this study was to determine the transcriptome and...
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