Article
Quantum dots affect expression of CD133 surface antigen in melanoma cells.
International journal of nanomedicine - 1 Jan 2011
Steponkiene Simona, Kavaliauskiene Simona, Purviniene Rasa, Rotomskis Ricardas, Juzenas Petras
Abstract excerpt
BACKGROUND: In novel treatment approaches, therapeutics should be designed to target cancer stem cells (CSCs). Quantum dots (QDs) are a promising new tool in fighting against cancer. However, little is known about accumulation and cytotoxicity of QDs in CSCs. METHODS: Accumulation and cytotoxicity of CdTe-MPA (mercaptopropionic acid) QDs in CSCs were assessed using flow cytometry and fluorescence-activated cell...
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