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Dedifferentiation-reprogrammed mesenchymal stem cells with improved therapeutic potential.

Stem cells (Dayton, Ohio) - 1 Dec 2011

Liu Yang, Jiang Xiaohua, Zhang Xiaohu, Chen Rui, Sun Tingting, Fok Kin Lam, Dong Jianda, Tsang Lai Ling, Yi Shaoqiong, Ruan Yechun, Guo Jinghui, Yu Mei Kuen, Tian Yuemin, Chung Yiu Wa, Yang Mo, Xu Wenming, Chung Chin Man, Li Tingyu, Chan Hsiao Chang

Abstract excerpt

Stem cell transplantation has been shown to improve functional outcome in degenerative and ischemic disorders. However, low in vivo survival and differentiation potential of the transplanted cells limits their overall effectiveness and thus clinical usage. Here we show that, after in vitro induct...

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Identifiers

PMID: 22052697
DOI: 10.1002/stem.764

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22052697-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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