Article
Evidence for genetic susceptibility to developing early childhood diarrhea among shantytown children living in northeastern Brazil.
The American journal of tropical medicine and hygiene - 1 Nov 2011
Pinkerton Relana C, Oriá Reinaldo B, Kent Jack W, Kohli Anita, Abreu Claudia, Bushen Oluma, Lima Aldo A M, Blangero John, Williams-Blangero Sarah, Guerrant Richard L
Abstract excerpt
To explore the genetic components of susceptibility to early childhood diarrhea (ECD), we used a quantitative genetic approach to estimate the heritability of ECD among children from two Brazilian favelas. Shared environment was used to model common exposure to environmental factors. Genetic relatedness was determined from pedigree information collected by screening household participants (n = 3,267) from two...
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