Identification of interspecies interactions affecting<i>Porphyromonas gingivalis</i>virulence phenotypes

Abstract excerpt

BACKGROUND: Periodontitis is recognized as a complex polymicrobial disease, however, the impact of the bacterial interactions among the 700-1,000 different species of the oral microbiota remains poorly understood. We conducted an in vitro screen for oral bacteria that mitigate selected virulence phenotypes of the important periodontal pathogen, Porphyromonas gingivalis. METHOD: We isolated and identified oral...

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