Article
The food-contaminant deoxynivalenol modifies eating by targeting anorexigenic neurocircuitry.
PloS one - 1 Jan 2011
Girardet Clémence, Bonnet Marion S, Jdir Rajae, Sadoud Medhi, Thirion Sylvie, Tardivel Catherine, Roux Julien, Lebrun Bruno, Wanaverbecq Nicolas, Mounien Lourdes, Trouslard Jérôme, Jean André, Dallaporta Michel, Troadec Jean-Denis
Abstract excerpt
Physiological regulations of energy balance and body weight imply highly adaptive mechanisms which match caloric intake to caloric expenditure. In the central nervous system, the regulation of appetite relies on complex neurocircuitry which disturbance may alter energy balance and result in anorexia or obesity. Deoxynivalenol (DON), a trichothecene, is one of the most abundant mycotoxins found on contaminated...
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