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Article

Zebrafish (Danio rerio) as a screen for attenuation of Lancefield group C streptococci and a model for streptococcal pathogenesis.

Veterinary pathology - 1 May 2013

Borst L B, Patterson S K, Lanka S, Suyemoto M M, Maddox C W

Abstract excerpt

Group C streptococci are highly contagious pyogenic bacteria responsible for respiratory tract, lymph node, urogenital tract, and wound infections. Wild-type strains of Streptococcus equi ssp equi (S. equi) and Streptococcus equi ssp zooepidemicus (S. zoo) as well as a commercially available modified live vaccine strain of S. equi were evaluated for virulence in zebrafish. Survival times, histologic lesions, and...

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PMID: 21997564
DOI: 10.1177/0300985811424731

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