Article
[Immunologic prognosis in hemoblastoses in children].
Voprosy onkologii - 1 Jan 1990
Tupitsyn N N, Kadagidze Z G, Baryshnikov A Iu, Makhonova L A, Maiakova S A, Kiselev A V, Peterson I S, Morozova O V, Gordina G A, Sholokhova E N
Abstract excerpt
The diagnostic value of monoclonal antibodies is discussed. The expression of ICO-GM1 and ICO-G2 myeloid antigens in pediatric patients with nonlymphoblastic leukemia was associated with poor prognosis whereas patients with the expression of T-cell markers fared better. The prognostic value of the antigens was not altered by brief cytotoxic treatment. The prognosis for non-T-cell ICO-II+ type childhood...
Topics
- Antibodies, Monoclonal
- Antigens, Neoplasm
- Biomarkers, Tumor
- Child
- Fluorescent Antibody Technique
- Humans
- Immunoenzyme Techniques
- Leukemia, Myeloid, Acute
- Lymphoma, Non-Hodgkin
- Phenotype
- Prognosis